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In group B rabbits some of the epididymal ductules were empty of mature spermatozoa, and others had low density of spermatozoa and sloughed germ cells in their lumina (Figure 3c,d). Epididymal ductules of group C rabbits were free from mature spermatozoa, and some cauda epididymal ductules contained sloughed germ cells (Figure 3e,f). Table 2 shows that the index weight of the testes and epididymis was decreased significantly (P ≤ 0.05) in BOL-treated groups compared with the control group. No significant changes were found in the index weight of the prostates. Moreover, there was a significant reduction (P ≤ 0.05) in the serum testosterone level in the groups B and C compared with the control group. Boldebolin steroids are a type of anabolic steroid that contain the active ingredient boldenone undecylenate.
- World wide Deca is one of the most popular injectable steroids.
- This same effect has been seen in many athletes as well as body-builders.
- The doses of BOL were calculated according to Paget and Barnes (1964).
- Unfortunately for many competitive athletes, this makes Deca and other nandrolone products off-limits.
The mechanism for this effect may occur by stimulating erythropoeitic stimulating factor, stimulates the release of erythropoietin in the kidneys. Anabolics can cause nitrogen, sodium, potassium and phosphorus retention and decrease the urinary excretion of calcium. The activity of boldenone is mainly anabolic, with a low androgenic potency.
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Trace amounts of the drug can easily be detected for months after discontinued use. Histopathological findings of testes, epididymis and prostate gland were evaluated under light microscopy. Incidence and severity of lesions in BOL-treated groups are summarized in (Table 4). Testes, epididymis and prostate glands were collected, weighed (as outlined above) and fixed rapidly in 10% neutral-buffered formalin for at least 24 h. The fixed specimens were processed through the conventional paraffin-embedding technique (Culling 1983), sectioned at 5 μm and stained with Mayer’s haematoxylin and eosin (HE). Blood was collected from the ear vein of each rabbit before euthanasia.
The doses of BOL were calculated according to Paget and Barnes (1964). Thirty white New Zealand mature male rabbits, 9–9.5 months of age, were housed in metal cages. Fed pelleted commercial feed (Ibex Co., Cairo, Egypt) and https://mitsikeli.com/2023/09/29/uk-fitness-enthusiasts-seek-optimal-results-with/ water was supplied without restriction. Rabbits in all groups received humane care in compliance with the animal care guidelines of the National Institute of Health, and the local ethical committee approved this study.
Body weight and body weight gain
Anabolic androgenic steroids (AAS) are synthetic derivatives of the male testosterone hormone that have been modified to improve their anabolic rather than androgenic activity (Shahidi 2001). The anabolic effects of AAS promote protein synthesis, muscle growth and erythropoiesis (Mottram & George 2000). Hence, AAS are used to enhance strength and durability of canine, equine and human athletes (Teale & Houghton 1991; Schänzer & Donike 1992; Schänzer 1996). Boldenone (BOL) is an anabolic steroid that differs from testosterone only by one double bond at the 1- position (Stolker et al. 2007) (Figure 1). It is used mainly as undecylenate ester by bodybuilders and is administered illegally to racing horses.
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No detectable changes were noticed in both treated groups apart from some moderate tubular dilatation (Figure 4b,c). The initial bwt of all groups was equalized approximately. Treatment with BOL had no significant effect on the final bwt and the bwt gain of the treated groups compared with the control group (Table 1). Yes, women can use Boldebolin steroids, but lower dosages are recommended in order to avoid virilization effects like increased body hair and deepening of the voice. Nandrolone is the molecule of Deca-Durabolin known to be a very highly anabolic and androgenic steroid. Deca-Durabolin enables to gain a large mass and strength accompanied by a slight fat loss.
Semen collection and sperm characteristics
Serum was separated for assessment of the total serum testosterone according to Demetriou (1987) using solid-phase radioimmunoassay (RIA) kits. This assay was based on presence of a testosterone-specific antibody immobilized to the wall of the polypropylene tube. Rabbits were ranked by restricted randomization procedures that approximately equalized the initial bwts among the different groups. They were then weighed weekly until the end of the experiment. Deca Durabolin is known to have a long lasting effect and as such injections of the steroid are given a week apart regardless of the total dose required. For this reason it is also recommended that it be used for no less than ten weeks and normally for 12 weeks.
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Supply and demand for Deca Durabolin is, as one can imagine, high. As such it is a relatively inexpensive product especially when sourced from an underground lab. Its ability to improve collagen synthesis is just one of the fascinating properties in Deca. It also improves bone mineral content which every athlete who suffers from connective tissue problems or joint issues finds invaluable. This could be due to it being a progestin which offers beneficial effects on immune mediated anti-inflammatory processes.
These can include acne, hair loss, increased body hair growth, and a deepening of the voice in women. More serious side effects can include liver damage and cardiovascular problems. There is an injectable anabolic steroid on the market which has a relatively positive history. It is commonly referred to as ‘Deca’ and has been used successfully in treating HIV+ and AIDS. Deca Durabolin is also known as being an incredible steroid when it comes to building muscle mass. It is commonly taken in conjunction with other types of steroids and these include Tren.